Abstracts

Information biology

One of the possible mechanism poroviding for the conservation of protein structure and function in the course of evolution is co-ordinated residue's substitutions. They occur in corellated manner such that disruptive effect of one mutation could be compensated by substitution of other residue(s). We analysed such substitutions in several protein families. Possible roles of co-ordinated substitutions is discussed.

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©2001, Siberian Branch of Russian Academy of Science, Novosibirsk
©2001, United Institute of Computer Science SB RAS, Novosibirsk
©2001, Institute of Computational Techologies SB RAS, Novosibirsk
©2001, A.P. Ershov Institute of Informatics Systems SB RAS, Novosibirsk
©2001, Institute of Mathematics SB RAS, Novosibirsk
©2001, Institute of Cytology and Genetics SB RAS, Novosibirsk
©2001, Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk
©2001, Novosibirsk State University
Last modified 06-Jul-2012 (11:45:21)