Information biology
Transcription Regulatory Regions Database (TRRD) is maintained at the Institute of Cytology and Genetics SB RAS (Novosibirsk, Russia) since 1993.
TRRD accumulates experimental information on the structure-function features of regulatory regions of eukaryotic genes. To input the information into the database, experts in biology annotate publications on the relevant experimental data.
Each TRRD entry corresponds to a particular gene and contains descriptions of several hierarchical levels of transcription regulation, including (1) transcription factor binding sites, (2) regulatory units (promoters, enhancers, and silencers), and (3) regulatory regions (3' and 5' regulatory regions, exons, and introns). Description of each regulatory level may contain both its structural characteristics (sequence, localization, etc.) and functional properties (effect on transcription activity of a gene; cell-cycle phase or ontogenetic stage specificity; cell type, tissue, or organ specificity, etc.).
In the database, the data on regulatory regions of a gene are supplemented with (1) descriptions of transcription factors used in the experiments on either binding capacities or functional activities of the corresponding sites, (2) patterns of regulation of gene expression, and (3) references to original publications.
TRRD is a module of GeneExpress system.
It is available at http://wwwmgs.bionet.nsc.ru/mgs/gnw/trrd/
Full Text in Russian: | HTML |
Comments |
[Home] [Conference] |
©2001, Siberian Branch of Russian Academy of Science, Novosibirsk
©2001, United Institute of Computer Science SB RAS, Novosibirsk
©2001, Institute of Computational Techologies SB RAS, Novosibirsk
©2001, A.P. Ershov Institute of Informatics Systems SB RAS, Novosibirsk
©2001, Institute of Mathematics SB RAS, Novosibirsk
©2001, Institute of Cytology and Genetics SB RAS, Novosibirsk
©2001, Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk
©2001, Novosibirsk State University
Last modified 06-Jul-2012 (11:45:21)